Mayank Garg | Tackling Acute Respiratory Distress Syndrome (ARDS) : Integrated and Holistic Approaches

When Monday July 22nd 2:00pm
Where: HDSI MPR 123
Zoom Info: http://bit.ly/HDSI-Seminars

Title: “Tackling Acute Respiratory Distress Syndrome (ARDS) : Integrated and Holistic Approaches”

Abstract: ARDS is a complex heterogenous disorder which forms a significant health care burden. Pathophysiologically, ARDS is caused by multiple aetiologies which can lead to the diversity in clinical presentation seen. In our work with preclinical rodent models, we investigate the role of host mitochondrial factors in skewing the inflammation resolution pathways leading to an aggravated and exaggerated state of inflammation and possibly increased mortality. This work elicits another instance of how endotype identification is essential in ARDS (and other diseases), to improve translation of basic research. A potential solution for this could be integration of data driven approaches to derive biological insights which would serve as essential context for preclinical disease models.

Mayank Garg Bio: Mayank is a physician scientist who completed his medical graduation and clinical training from IPGME&R and SSKM Hospital, Kolkata, India. He gained brief experience in intensive care before switching to experimental research at CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), Delhi, India. He is affiliated with Ashoka University as a Simons Ashoka Early Career fellow.

Mayank is currently pursuing quantitative health research to explore the heterogeneity of ICU disorders like Sepsis and ARDS. Realising the importance of context in biomedical research, he aims to derive mechanisms to leverage data science in a clinically relevant manner, and to validate them using contextual application of experimental models.

He also believes in the potential of digital transformation in personal empowerment, for improving health-care, sick-care, and clinical research. He is collaborating on a project to develop a digital framework to assist data collection and aid analysis for personalized lifestyle medicine. He plans to leverage the power of LLMs integrated with such digital frameworks for healthcare and healthcare research. He strongly advocates for collaborative growth and strict ethical standards as the foundation for advancing science.